![]() ![]() Employing combinatorial CRISPR, CombiGEM enables experimental confirmation of how genes and gene combinations relate to disease in supercharged fashion.Įngine has engineered NetMAPPR to operate in predict-test-learn cycles and scale for many research and drug discovery programs. NetMAPPR is Engine's searchable biology platform, revealing gene combinations and drug targets integral to diseases. Two scientific innovations lie at the heart of Engine Biosciences: NetMAPPR and CombiGEM. “Considering the field’s tremendous needs for the right drug targets for the right patients and Engine’s unique capabilities in finding those, we continue to be excited by Engine’s potential to power new medicines.” “We believe Engine's AI-enabled technology platform has the potential to discover new biology targets and disease-causing links amongst known targets,” said Leon Chen, CEO and Founding Partner of 6 Dimensions Capital. Through collaborations, Engine has also demonstrated its platform’s applicability in other disease areas and will continue to enable new therapeutics for more patients. Engine’s growing and advancing pipeline of targeted therapies for genetically-defined patient populations has shown promise in treating liver, ovarian, colorectal, and breast cancers, representing major areas of unmet medical need and, in total, approximately 2.5 million deaths every year. We are excited to be part of this next step with the team.”Įngine has performed several large-scale computational and experimental cycles with respect to genetic interactions and their relevance to multiple cancers, yielding new and subsequently validated discoveries. “Engine’s distinct combination of biology, technology, and drug discovery, as well as its global perspective, may well enable the company to be particularly capable of realizing the promise of artificial intelligence in drug discovery and tackling a wide variety of diseases. “The past year has reinforced the importance of rapid innovation and adaptation,” said Polaris Partners’ Amy Schulman. It will utilize the new funds to expand its portfolio of precision oncology therapeutics, prepare for its first clinical programs, and scale its proprietary technology platform. ![]() “We are honored that this preeminent group of life science and technology investors has recognized the progress our team has made and is supporting our mission to unleash new medicines by deciphering biology.”Įngine has already been progressing its novel biology findings into drug discovery programs and proprietary small molecule inhibitors. #Proprietary risk engine singapore code#The fundamental question continues to be whether we know the disease-driving errors in the genetic code of biology to direct these tools, including therapeutics,” said Jeffrey Lu, Engine Biosciences’ Co-Founder and CEO. “Many breakthrough tools to edit, program, and modulate biology have emerged and matured in recent years. Additionally, the company generates important insights for precision medicine applications. Engine’s technologies enable researchers and drug developers to uncover the gene interactions and biological networks underlying diseases orders-of-magnitude faster and more cost-effectively than conventional methods. Located in Singapore and Silicon Valley, Engine has been operating at the intersection of data science, machine learning, high-throughput biology experimentation, combinatorial genetics, chemistry, and drug discovery. Engine has now raised $53 million to date, including $10 million in a 2018 seed round. Amy Schulman, Managing Partner at Polaris Partners, has joined the Engine Biosciences Board of Directors. #Proprietary risk engine singapore series#Existing investors also participated in the Series A, which included 6 Dimensions Capital, WuXi AppTec, DHVC, EDBI, Baidu Ventures, Vectr Ventures, Goodman Capital, WI Harper, and Nest.Bio. This round was led by Polaris Partners and also included new investors Invus and one of the world’s premier institutional investors, based in Singapore. Engine identifies errors in the complex genetic codes of diseases, fixing them with precise therapeutic solutions. SINGAPORE & SAN CARLOS, Calif.-( BUSINESS WIRE)- Engine Biosciences (“Engine”) today announced the successful completion of an oversubscribed $43 million Series A funding round. ![]()
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